Postdoctoral Fellow, Translational Medicine Oncology, Yadav Lab

Job description

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech.

A Postdoctoral fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Mahesh Yadav in the Translational Medicine Oncology department at Genentech. Dr. Yadav’s lab focuses on understanding and monitoring anti-tumor specific T cell responses to track treatment outcomes and inform clinical decisions, and discovering novel tumor antigens for cancer vaccines. This position will focus on mapping the repertoire of T cell receptors (TCRs) against tumor antigens and using this as a tool to identify and validate various classes of tumor antigens. It will also involve using advanced technologies such as single-cell sequencing (CITE-seq) and spatial transcriptomics on clinical specimens for monitoring T cell responses.  This postdoctoral position will provide an opportunity to contribute to the exciting cancer vaccine pipeline in gRED. Candidates familiar with T cell immunology, TCR sequencing, and computational analysis are especially encouraged to apply.

The Opportunity:

• Discovery and Research: Identification and mapping of antigen-specific T cells/TCRs to track longitudinal T cell dynamics

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