Senior Automation/Medicinal Chemist

Job description

The Impact You’ll Make

We are seeking an experienced Senior Scientist in Automation/Medicinal Chemistry to accelerate our internal and partnership drug discovery portfolio. This role, bridging AI-enabled design and cutting-edge automated synthesis, is central to our mission.

Operating our Milton Park site, you will take ownership for delivery of compounds through our state-of-the-art Automation Studio and, by collaborating closely with drug designers, drive impactful outcomes for drug discovery programs within our pipeline.

You will have a track record of leadership from the lab, and combine deep medicinal and synthetic chemistry expertise with a commitment to modernizing the drug discovery process. A self-starter who can lead effectively from the bench and operate strategically.

In this role, you will:

• Design, prioritise, and tactically execute synthetic routes for small‑molecule targets, strategically using our Chemistry Automation Platform, our well-equipped traditional synthesis laboratories and CRO support to meet project goals on tight timelines.
• Build a strong collaborative partnership with computational and medicinal chemists to use the full capabilities of both the Centaur Chemist (design) and Chemistry Automation (synthesis) platforms including optimising methodologies, workflows, and best practices.
• Adapt core synthetic medicinal chemistry tactics onto the automation platform by collaborating with software developers and module owners, validating feasibility, defining safe and scalable conditions, and documenting processes clearly for reuse.
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