senior software engineering Technical Lead hybrid · Posted May 18, 2026
$116,900 – $217,100
USD per year

About this role

Genentech is hiring a senior-level Technical Lead in the software engineering function based in Holly Springs, NC. The posting calls out experience with Agile, Data Analytics. Compensation is listed at $116,900–$217,100 per year.

Role
Technical Lead
Function
software engineering
Level
senior
Track
hybrid
Employment
Full-time
Location
Holly Springs, NC
Department
Manufacturing & Engineering
Posted
May 18, 2026

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Job description

from Genentech careers

The Position

Welcome to Holly Springs, North Carolina— home to Genentech's largest-ever investment with an ambitious goal to be a fully connected Plant of the Future. This is where next-generation technology, capability, digital connectivity and Operational Excellence converge to create the global standard for high-volume, highly-efficient Drug Product manufacturing. This will include Component Prep & Compounding, Liquid PFS Filling, Automated Inspection, Autoinjector Assembly, Packaging/Finished Products.

The facility's core is defined by innovation - leveraging advanced automation, robotics, digital tools, real-time data analytics, and simple, streamlined processes to produce the highest quality medicines. This plant will not only meet today’s demand for CVRM (Cardiovascular, Renal, and Metabolism) medicines but is a strategic commitment to be scalable with this portfolio, which serves one of the largest patient populations in the world. This is a fast-paced, highly entrepreneurial environment with a high-level of accountability from the site team to launch operations in 2028. 

Are you a problem-solver and change agent who thrives in a High-Performing Team environment, eager to tackle the most complex manufacturing challenges? If so, this is a once-in-a-lifetime opportunity to not only launch a state-of-the-art facility from the ground-up but to shape the culture of our organization for the next generation. 

This is an excerpt. Read the full job description on Genentech careers →
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