Senior Principal Engineer, Inspection
Genentech · Holly Springs, NC · Manufacturing & Engineering
About this role
Genentech is hiring a principal-level Principal Engineer in the software engineering function based in Holly Springs, NC. The posting calls out experience with Data Analytics. Compensation is listed at $114,400–$212,400 per year.
- Role
- Principal Engineer
- Function
- software engineering
- Level
- principal
- Track
- Tech leadership
- Employment
- Full-time
- Location
- Holly Springs, NC
- Department
- Manufacturing & Engineering
- Posted
- Apr 23, 2026
More roles at Genentech
Job description
from Genentech careersThe Position
Welcome to Holly Springs, North Carolina— home to Genentech's largest-ever investment with an ambitious goal to be a fully connected Plant of the Future. This is where next-generation technology, capability, digital connectivity and Operational Excellence converge to create the global standard for high-volume, highly-efficient Drug Product manufacturing. This will include Component Prep & Compounding, Liquid PFS Filling, Automated Inspection, Autoinjector Assembly, Packaging/Finished Products.
The facility's core is defined by innovation - leveraging advanced automation, robotics, digital tools, real-time data analytics, and simple, streamlined processes to produce the highest quality medicines. This plant will not only meet today’s demand for CVRM (Cardiovascular, Renal, and Metabolism) medicines but is a strategic commitment to be scalable with this portfolio, which serves one of the largest patient populations in the world. This is a fast-paced, highly entrepreneurial environment with a high-level of accountability from the site team to launch operations in 2028.
Are you a problem-solver and change agent who thrives in a High-Performing Team environment, eager to tackle the most complex manufacturing challenges? If so, this is a once-in-a-lifetime opportunity to not only launch a state-of-the-art facility from the ground-up but to shape the culture of our organization for the next generation.