Principal Machine Learning Engineer
Genentech · South San Francisco, CA · Data Science & AI / ML
About this role
Genentech is hiring a principal-level Machine Learning Engineer based in South San Francisco, CA. The posting calls out experience with TensorFlow, PyTorch, scikit-learn, MLOps. Compensation is listed at $231,280–$429,520 per year.
- Role
- Machine Learning Engineer
- Function
- machine learning
- Level
- principal
- Track
- Tech leadership
- Employment
- Full-time
- Location
- South San Francisco, CA
- Department
- Data Science & AI / ML
- Posted
- Mar 6, 2026
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Job description
from Genentech careersThe Position
Why Genentech
We’re passionate about delivering on Our Promise to improve the lives of patients and create healthier communities for all. We foster a culture of inclusivity, integrity and creativity while boldly pursuing answers to the world’s most complex health challenges and transforming society.
Who We Are
Our Data, Analytics, and AI team is dedicated to solving complex healthcare challenges and improving patient outcomes. Data, Analytics, and AI empowers business partners across Commercial, Medical, and Government Affairs (CMG) to make impactful decisions by leveraging data, analytics, business products, and AI/ML to enable fast, targeted actions in rapidly evolving business contexts.
Data, Analytics, and AI fosters a unified understanding of customers, actions, and outcomes by integrating analytics and insights seamlessly into CMG’s evolving digital, data, and automation platforms, creating scalable solutions and eliminating silos.
In Data, Analytics, and AI, you will work as a trusted, objective advisor and expert, recommending critical decisions and actions to be taken with credibility and a focus on driving measurable impact. You will be part of a thriving culture built on collaboration and innovation.
Job Summary