Principal Engineer/Tech Lead - Instrument Integration, Engineering - Lab Automation
Genentech · South San Francisco, CA · Research & Development
About this role
Genentech is hiring a principal-level Principal Engineer in the software engineering function based in South San Francisco, CA. The posting calls out experience with Python, Java, AWS, Distributed Systems. Compensation is listed at $162,600–$302,000 per year.
- Role
- Principal Engineer
- Function
- software engineering
- Level
- principal
- Track
- Tech leadership
- Employment
- Full-time
- Location
- South San Francisco, CA
- Department
- Research & Development
- Posted
- Apr 2, 2026
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Job description
from Genentech careersThe Position
A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.
Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.
The Opportunity